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Cars are fusion proteins composed of an extracellular portion that is usually derived from an antibody and intracellular signaling modules derived from tcell signaling proteins. In this review, we focus on (i) the prospects for universal car t cells, (ii) the use of car t cell therapy for solid tumors, and (iii) emerging disparities in the use.

Considering that stat3 signaling plays a pivotal role in numerous biological processes in the development of both solid and hematologic malignancies, it is also. This also suggests that future engineering could isolate individual signaling motifs to enhance specific t cell phenotypes and create synthetic combinatorial domains that are optimized for specific. The review highlights future directions and.

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